𝔖 Bobbio Scriptorium
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Crossing the barrier: Targeting epithelial receptors for enhanced oral vaccine delivery

✍ Scribed by Bert Devriendt; Bruno G. De Geest; Bruno M. Goddeeris; Eric Cox


Book ID
113695052
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
365 KB
Volume
160
Category
Article
ISSN
0168-3659

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Background Following receptor-mediated endocytosis, vector/DNA complexes require assistance to exit endocytic vesicles in order to avoid degradation in the lysosomes. Overcoming this barrier is a major challenge for the development of receptor-targeted, non-viral gene delivery. ## Methods The fus