Cross-species neural grafting in a rat model of Parkinson's disease
✍ Scribed by Björklund, Anders; Stenevi, Ulf; Dunnett, Stephen B.; Gage, Fred H.
- Book ID
- 109727245
- Publisher
- Nature Publishing Group
- Year
- 1982
- Tongue
- English
- Weight
- 647 KB
- Volume
- 298
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/298652a0
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📜 SIMILAR VOLUMES
Parkinson's disease (PD) is caused by dopamine (DA) depletion consequent to cell degeneration in the substantia nigra pars compacta (SNc) and the ventral tegmental area (VTA). Although computational analyses of PD have focused on DA depletion in DA-recipient parts of the basal ganglia, there is also
## Abstract ## Purpose To measure intra‐ and inter‐hemispheric connectivity within the basal ganglia (BG) nuclei in healthy and in unilateral 6‐hydroxydopamine (6‐OHDA) Parkinson disease rat model in order to test the BG interhemispheric connectivity hypothesis. ## Material and Methods The manga