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Cross-regulation of cannabinoid CB1 and CB2 receptors governs hepatic steatosis

✍ Scribed by Ying-Ying Yang; Han-Chieh Lin

Book ID
111239390
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
105 KB
Volume
30
Category
Article
ISSN
0106-9543

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Endogenous cannabinoids acting at CB1 receptors stimulate appetite, and CB1 antagonists show promise in the treatment of obesity. CB1؊/؊ mice are resistant to diet-induced obesity even though their caloric intake is similar to that of wild-type mice, suggesting that endocannabinoids also regulate fa