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Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain

✍ Scribed by Condliffe, Daniel; Wong, Andrew; Troakes, Claire; Proitsi, Petroula; Patel, Yogen; Chouliaras, Leonidas; Fernandes, Cathy; Cooper, Jonathan; Lovestone, Simon; Schalkwyk, Leonard; Mill, Jonathan; Lunnon, Katie

Book ID
123595575
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
923 KB
Volume
35
Category
Article
ISSN
0197-4580

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## Abstract ## Objective Executive deficits are common in patients with Alzheimer's disease (AD), contribute prominently to clinical disability, and may be associated with frontal lobe pathology. This study examined regional brain hypometabolism associated with executive dysfunction in patients wi