Cytoplasmic superoxide causes bone fragi
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Hidetoshi Nojiri; Yoshitomo Saita; Daichi Morikawa; Keiji Kobayashi; Chizuru Tsu
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Article
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2011
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American Society for Bone and Mineral Research
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English
β 976 KB
The aging process correlates with the accumulation of cellular and tissue damage caused by oxidative stress. Although previous studies have suggested that oxidative stress plays a pathologic role in the development of bone fragility, little direct evidence has been found. In order to investigate the