Cross-Linked Multilayers of Poly(vinyl amine) as a Single Component and Their Interaction with Proteins
✍ Scribed by Ecaterina S. Dragan; Florin Bucatariu
- Book ID
- 102494631
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 491 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1022-1336
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Novel multilayer thin films that consist solely of cross‐linked single component layers are generated by a selective cross‐linking of the poly(vinyl amine) (PVAm) layers in [PVAm/poly(acrylic acid) (PAA)]~n~ thin films constructed either on silica particles or silicon wafers, followed by the removal of PAA. The surface topography of the (PVAm)~n~ multilayer thin films, before and after the adsorption of human serum albumin (HSA), has been studied by atomic force microscopy on the freeze‐dried films. The decrease of the average roughness of the film after the adsorption of HSA showed the protein was adsorbed into the (PVAm)~n~ film making these films potential reservoirs for proteins.
magnified image