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Cross-genotype-reactivity of the immunodominant HCV CD8 T-cell epitope NS3-1073

✍ Scribed by P. Fytili; G.N. Dalekos; V. Schlaphoff; P.V. Suneetha; C. Sarrazin; W. Zauner; K. Zachou; T. Berg; M.P. Manns; C.S. Klade; M. Cornberg; H. Wedemeyer


Book ID
116960628
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
993 KB
Volume
26
Category
Article
ISSN
0264-410X

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Human leukocyte antigen B27 (HLA-B27) is associated with protection in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infection. This protective role is linked to single immunodominant HLA-B27-restricted CD8+ T-cell epitopes in both infections. In order to define the relative contrib