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Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection

✍ Scribed by Wakim, Linda M.; Bevan, Michael J.


Book ID
109900446
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
768 KB
Volume
471
Category
Article
ISSN
0028-0836

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## Abstract Dendritic cells (DC) generated after a short‐term exposure of monocytes to IFN‐α and GM‐CSF (IFN‐DC) are highly effective in inducing cross‐priming of CD8^+^ T cells against viral antigens. We have investigated the mechanisms responsible for the special attitude of these DC and compared