Background: Environmental factors of the modern Western lifestyle may trigger Crohn's disease (CD) in susceptible individuals. Because such factors could be part of ingested matter, we intended to improve intestinal Crohn's lesions by exclusion thereof. Methods: At first we tested a highly restrict
Crohn's disease: Ingested matter matters
β Scribed by Gergor Bartel; Ilse Weiss; Christoph Gasche
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 34 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1078-0998
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β¦ Synopsis
Kiddell et al 1 provide a literature overview on the role of diet in the development of Crohn's disease (CD). Although the authors value the importance of nutrition for gastrointestinal homeostasis and microbiota, they were unable to find sufficient evidence that supports a direct relationship between diet and CD. Their conclusion might have been different if they had read our recent controlled study that was published in the same journal 2 years earlier. 2 This ''medieval diet study'' demonstrated mucosal improvement (assessed by endoscopy and MRI) within 6 weeks. It was a highly restrictive diet that allowed only certain spelt bread and red meat (both derived from intensively monitored organic farming) and rigorously excluded all other food
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