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Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1/2 signalling pathway

✍ Scribed by Jun Cai; Fang-Fang Yi; Zhou-Yan Bian; Di-Fei Shen; Long Yang; Ling Yan; Qi-Zhu Tang; Xin-Chun Yang; Hongliang Li

Book ID
114778816
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2010
Tongue
English
Weight
404 KB
Volume
14
Category
Article
ISSN
1582-1838

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## Abstract Macrophages are critically involved in the pathogenesis of genetically caused demyelination, as it occurs in inherited demyelinating neuropathies. On the basis of the observation that upregulation of the Schwann cell‐derived chemokine MCP‐1 (CCL2) is a pathologically relevant mechanism