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Critical role of TNF-alpha-TNFR1 signaling in intracranial aneurysm formation

✍ Scribed by Aoki, Tomohiro; Fukuda, Miyuki; Nishimura, Masaki; Nozaki, Kazuhiko; Narumiya, Shuh


Book ID
125405114
Publisher
Springer (Biomed Central Ltd.)
Year
2014
Tongue
English
Weight
321 KB
Volume
2
Category
Article
ISSN
2051-5960

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## Abstract Matrix metalloproteinases (MMPs), in particular MMP‐9, have been shown to be induced by cytokines, including TNF‐α and contributes to airway inflammation. However, the mechanisms underlying TNF‐α‐induced MMP‐9 expression in human A549 cells remain unclear. Here, we report that TNF‐α‐ind