Critical role of NKT cell-derived IL-5 and eosinophils in liver injury induced by concanavalin a in mice
β Scribed by Hubert Louis; Alain Le Moine; Eric Quertinmont; Frederic Paulart; Nathalie Nagy; Veronique Flamand; Michel Goldman; Olivier Le Moine; Jacques Deviere
- Book ID
- 119429135
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 188 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0016-5085
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π SIMILAR VOLUMES
that infiltrating T cells are activated and produce inflamma-CD4 / T lymphocytes have been identified as being retory lymphokines. 3,4 In experimental autoimmune hepatitis, sponsible for organ damage in the murine model of ex-T-cell-mediated liver damage could be demonstrated. 5 Howperimental liver
The liver appears to play an important role in immunological tolerance, for example, during allo-transplantation. We investigated tolerance mechanisms in the model of concanavalin A (ConA)-induced immune-mediated liver injury in mice. We found that a single injection of a sublethal ConA dose to C57B