CD23-deficient and anti-CD23 monoclonal antibody-treated mice were used to investigate the role of the low-affinity receptor for IgE (CD23) in allergic airway inflammation and airway hyperresponsiveness (AHR). While there were no significant differences in ovalbumin (OVA)specific IgE titers and tiss
Critical role of microglial CD40 in the maintenance of mechanical hypersensitivity in a murine model of neuropathic pain
β Scribed by Ling Cao; Christopher D. Palmer; Jennifer T. Malon; Joyce A. De Leo
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 386 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The aims of this study were to investigate the occurrence of apoptotic cell death in the dorsal horn of the adult rat spinal cord following chronic constriction injury (CCI) to the sciatic nerve and to correlate this with behavioural responses. Six groups of six rats were used as follow
## Abstract CD30 is a costimulatory molecule of the TNF receptor superfamily, expressed on activated T and B cells. Previously, we have shown in a murine asthma model the crucial role of CD30 signaling for the development of this Th2βcellβmediated disease. In the present study, we investigated the
## Abstract Although spinal glia acquire a reactive profile in radiculopathy, glial cell proliferation remains largely unstudied. This study investigated spinal glial proliferation in a model simulating painful disc herniation; the C7 nerve root underwent compression and chromic gut suture exposure
Chimpanzees remain the only recognized animal model for the study of hepatitis C virus (HCV). Studies performed in chimpanzees played a critical role in the discovery of HCV and are continuing to play an essential role in defining the natural history of this important human pathogen. In the absence