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Critical role of ABCA1 transporter in sphingosine 1-phosphate release from astrocytes

✍ Scribed by Koichi Sato; Enkhzol Malchinkhuu; Yuta Horiuchi; Chihiro Mogi; Hideaki Tomura; Masahiko Tosaka; Yuhei Yoshimoto; Atsushi Kuwabara; Fumikazu Okajima

Book ID
111180495
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
348 KB
Volume
0
Category
Article
ISSN
0022-3042

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## Abstract The mitogenic role of sphingosine‐1‐phosphate (S1P) and its involvement in basic fibroblast growth factor (bFGF)‐induced proliferation were examined in primary cultures of cerebellar astrocytes. Exposure to bFGF resulted in a rapid increase of extracellular S1P formation, bFGF inducing