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Critical role for the immunoproteasome subunit LMP7 in the resistance of mice to Toxoplasma gondii infection

✍ Scribed by Liping Tu; Chikako Moriya; Takashi Imai; Hidekazu Ishida; Kohhei Tetsutani; Xuefeng Duan; Shigeo Murata; Keiji Tanaka; Chikako Shimokawa; Hajime Hisaeda; Kunisuke Himeno


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
491 KB
Volume
39
Category
Article
ISSN
0014-2980

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## Abstract Nod2 belongs to the nucleotide‐binding domain leucine‐rich repeat family of proteins and senses bacterial cell wall components to initiate innate immune responses against various pathogens. Recently, it has been reported that T‐cell‐intrinsic expression of Nod2 promotes host defense aga