Population stratification is an important potential confounder of genetic case-control association studies. For replication studies, limited availability of samples may lead to imbalanced sampling from heterogeneous populations. Genomic control (GC) can be used to correct w 2 test statistics which a
Critical evaluation of quadratic logistic discriminant analysis methods: A case study
β Scribed by E. Lesaffre; J.L. Willems; J. Pardaens; E.C. Van der Meulen
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 817 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0010-4809
No coin nor oath required. For personal study only.
β¦ Synopsis
Electrocardiographic measurements from two groups, patients with left ventricular hypertrophy and clinically normal cases, were analyzed to illustrate the performance of the linear logistic discrimination method in the case of very unequal covariance matrices. Two quadratic extensions of the linear model were critically investigated. The use of graphical methods to check the model has been stressed and illustrated. o 1985 Academic PXSS, ~nc.
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