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Critical effect of VEGF in the process of endothelial cell apoptosis induced by high glucose

✍ Scribed by Zhonghan Yang; Xuehua Mo; Qing Gong; Qiuhui Pan; Xia Yang; Weibin Cai; Chaoyang Li; Jian-xing Ma; Yunshao He; Guoquan Gao


Publisher
Springer
Year
2008
Tongue
English
Weight
679 KB
Volume
13
Category
Article
ISSN
1360-8185

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## Abstract Hyperglycemia is the hallmark of diabetes mellitus. Poor glycemic control is correlated with increased cardiovascular morbidity and mortality. High glucose can trigger endothelial cell apoptosis by de‐activation of endothelial nitric oxide synthase (eNOS). eNOS was recently demonstrated