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Critical care of the end-stage liver disease patient awaiting liver transplantation

✍ Scribed by James Y. Findlay; Oren K. Fix; Catherine Paugam-Burtz; Linda Liu; Puneet Sood; Stephen J. Tomlanovich; Jean Emond


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
177 KB
Volume
17
Category
Article
ISSN
1527-6465

No coin nor oath required. For personal study only.

✦ Synopsis


Patients with end-stage liver disease awaiting liver transplantation frequently require intensive care admission and management due to either complications of liver failure or to intercurrent illness, particularly infection. Mortality in such patients is high and the development of an illness necessitating intensive care unit management can influence transplant candidacy. Specialized support frequently requires hemodynamic support, mechanical ventilation, and renal support. In this review, areas of management of particular importance to patients with end-stage liver disease in the intensive care unit are discussed. These areas are hepatic encephalopathy, infectious diseases, cardiovascular support, mechanical ventilation, renal support and combined transplantation, and decisions regarding delisting. Current knowledge specific to these patients, when available, is discussed, current practice is described, and areas of uncertainty in the evidence are discussed.


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