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Critical aspects in reproductive and developmental toxicity testing of environmental chemicals

✍ Scribed by Jochen Buschmann

Book ID
113875039
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
119 KB
Volume
22
Category
Article
ISSN
0890-6238

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Developmental toxicity associated with r
Developmental toxicity associated with receptor tyrosine kinase Ret inhibition in reproductive toxicity testing
✍ George R. Clemens; Raymond E. Schroeder; Steven H. Magness; Elizabeth V. Weaver; πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 183 KB πŸ‘ 3 views

## Abstract ## BACKGROUND: Urogenital abnormalities are among the most common of all human birth defects. In developmental toxicity studies with the Syk kinase inhibitor R788, a spectrum of findings, including renal agenesis, were observed. R788 has also been found to inhibit the receptor tyrosine