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Criteria, mechanisms, and potency evaluation for tumor promoters: Dioxin as a model

โœ Scribed by Y.-h. Xu; Y.P. Dragan; R.R. Maronpot; T.L. Goldsworthy; H.C. Pitot


Book ID
116079306
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
230 KB
Volume
25
Category
Article
ISSN
0045-6535

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There is a growing need for short-term and cost-effective bioassay to assess the efficacy of potential chemo-preventive agents. We report that the induction of glutathione (GSH) S-transferase (mGSTP1-1) by a chemo-preventive agent can be used as a reliable marker to assess its efficacy in retarding