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Criteria for evaluating protein structures derived from comparative modeling

✍ Scribed by Česlovas Venclovas; Adam Zemla; Krzysztof Fidelis; John Moult

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
357 KB
Volume
29
Category
Article
ISSN
0887-3585

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✦ Synopsis

Following the first experiment for the Critical Assessment of methods for protein Structure Prediction (CASP1), numerical criteria were devised to analyze the performance of prediction methods. We report here the criteria for comparative modeling, and how effective they were in CASP2. These criteria are intended to evolve into a set of numerical measures that provide a comprehensive assessment of the quality of a structure produced by comparative modeling, and provide a means of investigating which modeling methods are most effective, so as to establish where future effort may be most productively applied. Pro-

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