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CREM deficiency in mice alters the response of bone to intermittent parathyroid hormone treatment

✍ Scribed by Fei Liu; Sun-Kyeong Lee; Douglas J. Adams; Gloria A. Gronowicz; Barbara E. Kream

Book ID
116319894
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
556 KB
Volume
40
Category
Article
ISSN
8756-3282

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## Abstract Parathyroid hormone (PTH) has biphasic effects on bone: continuous treatment is catabolic whereas intermittent treatment is anabolic. The mechanism(s) responsible for these differing effects are still unclear, partly because of the previous non‐availability of a model system in which ef