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CREM activator and repressor isoform expression in human male germ cells

✍ Scribed by SONJA BLÖCHER; LUDGER FINK; RAINER M. BOHLE; MARTIN BERGMANN; KLAUS STEGER

Book ID
108785156
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
235 KB
Volume
28
Category
Article
ISSN
0105-6263

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Cyclic AMP-responsive element modulator (CREM) is a transcription factor highly expressed in the post-meiotic germ cells of the testis. Its pivotal role is to regulate the expression of several germ cell-specific genes, a crucial function as demonstrated by the severe phenotype of mice whose CREM ge