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CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia

✍ Scribed by Inthal, A; Zeitlhofer, P; Zeginigg, M; Morak, M; Grausenburger, R; Fronkova, E; Fahrner, B; Mann, G; Haas, O A; Panzer-Grümayer, R


Book ID
121384203
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
480 KB
Volume
26
Category
Article
ISSN
0887-6924

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## Abstract Although it has been suggested that mutations of the __FLT3__, __NRAS__, __KRAS__, and __PTPN11__ genes are particularly frequent in high hyperdiploid (>50 chromosomes) pediatric acute lymphoblastic leukemias (ALLs), this has as yet not been confirmed in a large patient cohort. Furtherm