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CREB-Regulated Transcription Coactivator 1-Dependent Transcription in Alzheimer’s Disease Mice

✍ Scribed by Saura, Carlos A.

Book ID
119985607
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
107 KB
Volume
10
Category
Article
ISSN
1660-2854

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✍ Bruce A. Citron; John S. Dennis; Ross S. Zeitlin; Valentina Echeverria 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 155 KB 👁 1 views

## Abstract Altered gene expression occurs in central nervous system disorders, including Alzheimer's disease (AD). Transcription factor Sp1 may be involved insofar as it can regulate the expression of several AD‐related proteins, including amyloid precursor protein (APP) and tau. Sp1 could itself