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CREB is activated in smooth muscle cells isolated from atherosclerotic plaques and reduces smooth muscle cell proliferation via p21-dependent mechanism

✍ Scribed by Sun, Lan; Zhao, Rui; Bai, Yongyi; Cao, Ruihua; Wang, Fuyu; Yang, Shengqian; Qin, Zhizhen; Du, Guanhua

Book ID: 122211584
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 855 KB
Volume: 174
Category: Article
ISSN: 0167-5273
DOI: 10.1016/j.ijcard.2014.04.078

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## Abstract Smooth muscle cells (SMC) play a central role in common vascular pathologies such as atherosclerosis and restenosis. Understanding the molecular regulation of SMC proliferation at a transcriptional level may provide important clues for the targeted control of vascular hyperplasia. We re