Fine tuning of receptor-selectivity for
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Yasuhiro Abe; Tomoaki Yoshikawa; Masaki Inoue; Tetsuya Nomura; Takeshi Furuya; T
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Article
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2011
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Elsevier Science
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English
⚖ 415 KB
Tumor necrosis factor-a (TNF) is one of the attractive targets for the development of anti-inflammatory and anti-tumor drugs, because it is an important mediator in the pathogenesis of several inflammatory diseases and tumor progression. Thus, there is an increasing need to understand the TNF recept