𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Creation of chirality in the reaction of the chiral ester enolate-imine condensation leading to the stereodivergent synthesis of β-lactams

✍ Scribed by Makoto Shimizu; Yoshihiro Teramoto; Tamotsu Fujisawa

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
241 KB
Volume
36
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The asymmetric synthesis of β-lactam ant
The asymmetric synthesis of β-lactam antibiotics-v. Application of chiral α,β-epoxyimines in ketene-imine cycloaddition reactions leading to homochiral 3-aminoazetidinones.
✍ David A. Evans; J.Michael Williams 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 332 KB

Imines derived from chiral a$-epoxyaldehydes have been shown to be useful chiral glyoxal imine synthons in the ketene-imine cycloaddition reaction. This process, which proceeds with high levels of reaction diastereoselection, affords enantiomerically pure &-substituted 3-amino-4alkylazetidinones in

Chiral N-phosphonyl imine chemistry: asy
Chiral N-phosphonyl imine chemistry: asymmetric additions of malonate-derived enolates to chiral N-phosphonyl imines for the synthesis of β-aminomalonates
✍ Zhong-Xiu Chen; Teng Ai; Parminder Kaur; Guigen Li 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 179 KB

Chiral N-phosphonyl imines attached by 1-naphthyl group were found to react with lithium malonate enolates smoothly to give chiral b-aminomalonates. Good yields and excellent diastereoselectivity were achieved for sixteen examples. The chiral auxiliary can be readily removed by treating with trifluo