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Creating embryonic tissues: The role of the bHLH genes during the prepatterning of the mesoderm in Xenopus laevis

โœ Scribed by Patrick T. McMillen; Carolyn M. Gaydos; Ellen Moore; Thuy I. Vo; Kelly A. McLaughlin


Book ID
116976398
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
59 KB
Volume
306
Category
Article
ISSN
0012-1606

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The cell proliferative activity of the Myc family of basic helix-loop-helix/leucine zipper (bHLHZip) transcription factors is dependent upon binding to the ubiquitous Max protein. In the absence of heterodimerization with Max, Myc protein is unable to efficiently bind to DNA and activate transcripti