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Cre-Mediated Cerebellum- and Hippocampus-Restricted Gene Mutation in Mouse Brain

✍ Scribed by Huailian Guo; Chengjian Mao; Xiao-Lu Jin; Hong Wang; Yen-Te Tu; Prachee Pradeep Avasthi; Yuqing Li

Book ID
115585355
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
154 KB
Volume
269
Category
Article
ISSN
0006-291X

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## Abstract Summary: The neuron‐specific rat enolase (NSE) promoter was employed to establish transgenic mice expressing Cre recombinase in the central nervous system. Founders were crossed with dormant lacZ indicator mice and specificity as well as efficiency of Cre‐mediated transgene activation w