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Craniofacial variation and growth in the Prader-Labhart-Willi syndrome

✍ Scribed by F. John Meaney; Merlin G. Butler


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
474 KB
Volume
74
Category
Article
ISSN
0002-9483

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A 16-year-old boy with Prader-Labhart-Willi syndrome (PLWS) had hypotonia, feeding difficulties, failure to thrive, strabismus and bilateral inguinal hernias with cryptorchidism during infancy followed by hyperphagia, marked early-onset obesity with insulin-dependent diabetes mellitus and necrobiosi

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## Abstract Growth hormone (GH) therapy for short stature in patients with Prader–Willi syndrome (PWS) has started worldwide, and various favorable effects have been reported. However, the possibility of progression of scoliosis arises as a new problem of the GH therapy. In this study, we analyzed