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Craniofacial abnormalities induced by the ectopic expression of homeobox genes

✍ Scribed by Jenny Whiting

Book ID
114071376
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
539 KB
Volume
396
Category
Article
ISSN
0027-5107

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## Abstract Thalidomide and 13‐cis retinoic acid (RA) show anticancer effects as sole agents or in combination with other drugs. However, induction of homeobox (HOX) gene expression by 13‐cis RA may contribute to tumor progression thereby potentially limiting its efficacy. The purpose was to test i