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Cranial radiation therapy and damage to hippocampal neurogenesis

✍ Scribed by Michelle Monje

Publisher
Wiley (John Wiley & Sons)
Year
2008
Tongue
English
Weight
107 KB
Volume
14
Category
Article
ISSN
1940-5510

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✦ Synopsis

Abstract

Cranial radiation therapy is associated with a progressive decline in cognitive function, prominently memory function. Impairment of hippocampal neurogenesis is thought to be an important mechanism underlying this cognitive decline. Recent work has elucidated the mechanisms of radiation‐induced failure of neurogenesis. Potential therapeutic interventions are emerging. Β© 2008 Wiley‐Liss, Inc. Dev Disabil Res Rev 2008;14:238–242.

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