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CpG oligodeoxynucleotides stimulate cord blood mononuclear cells to produce immunoglobulins

✍ Scribed by Cheri D. Landers; Subbarao Bondada

Book ID: 116366355
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 192 KB
Volume: 116
Category: Article
ISSN: 1090-2341
DOI: 10.1016/j.clim.2005.04.013

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## Abstract The Toll-like receptor (TLR)9 is critical for the recognition of immunostimulatory CpG motifs but may cooperate with other TLRs. We analyzed TLR1–10 mRNA expression by using quantitative real-time PCR in highly purified subsets of human PBMC and determined the sensitivity of these subse