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CpG-conjugated apoptotic tumor cells elicit potent tumor-specific immunity

✍ Scribed by Hidekazu Shirota; Dennis M. Klinman

Book ID
105967874
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
582 KB
Volume
60
Category
Article
ISSN
0340-7004

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## Abstract Prophylactic tumor vaccination against subsequent tumor challenge depends on effective cross‐priming __in vivo__. Professional APCs process tumor antigens from whole tumor cells and present them to CD4^+^ and CD8^+^ T cells. Data suggest that dendritic cells process antigens more effici