𝔖 Bobbio Scriptorium
✦   LIBER   ✦

CP2TiCl2-catalyzed hydroalumination of internal alkynes: an access to (Z)-olefins

✍ Scribed by Arnaud Parenty; Jean-Marc Campagne

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
75 KB
Volume
43
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

The reduction of alkynols with LiAlH 4 in diglyme is a long known process leading to the formation of (E)-alkenols. We have, by serendipity, found that, in the presence of a catalytic amount (10%) of Cp 2 TiCl 2 , the stereoselectivity of the reaction is reversed, leading to the selective formation of the (Z)-alkenols. The scope and limitations of this methodology and a postulated catalytic cycle are also discussed.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: CP2TiCl2-Catalyzed
ChemInform Abstract: CP2TiCl2-Catalyzed Hydroalumination of Internal Alkynes: An Access to (Z)-Olefins.
✍ Arnaud Parenty; Jean-Marc Campagne πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v