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Coxsackie B3 virus encephalitis in a patient with agammaglobulinaemia

✍ Scribed by N. T. Hertel; F. K. Pedersen; C. Heilmann

Publisher
Springer
Year
1989
Tongue
English
Weight
154 KB
Volume
148
Category
Article
ISSN
0340-6997

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✦ Synopsis

A 19-month-old boy with agammaglobulinaemia contracted a Coxsackie B3 virus infection which caused meningoencephalitis. His neurological status deteriorated over the following 4 years and he died aged 6 years. Treatment with gammaglobulin i.m. and IgG-Fab2 fragments i.v. was not effective. Enterovirus can cause life-threatening infections in immunodeficient patients.

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From 1979 to 1981, a total of 910 cardiac patients and 776 noncardiac patients were studied and compared for evidence of coxsackie B virus infections. Of 78 cardiac patients with coxsackie B infection, 30 had pleurodynia, 18 myocarditis, and 20 pericarditis. The age-adjusted rates of infection per 1