Coxeter Groups, 2-Completion, Perimeter Reduction and Subgroup Separability

Stereo-divergent asymmetric total synthe

Stereo-divergent asymmetric total synthesis of avenaciolide and isoavenaciolide. Complete reversal of stereoselectivity in reduction of 2-vinyl aldols with / without trimethylsilyl directing group

✍ Keisuke Suzuki; Mayumi Miyazawa; Masato Shimazaki; Gen-ichi Tsuchihashi 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 253 KB

## Stereo-divergent asymmetric total synthesis of avenaciolide and isoavenaciolide was achieved via 1.2-rearrangement of chiral epoxyalcohol derivatives. where complete reversal of stereoselectivity with / without the TMS-directing group in the reduction of Z-vinyl aldols was used as the key branc