Combined effects of cyclooxygenase-1 and
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Tomohiro Kitamura; Masaki Itoh; Tetsuo Noda; Mamoru Matsuura; Keiji Wakabayashi
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Article
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2004
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John Wiley and Sons
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French
⚖ 88 KB
## Abstract As with cyclooxygenase (COX)‐2, genetic disruption of __COX‐1__ gene or pharmacologic inhibition of its activity has been shown to decrease the number of intestinal polyps in __Apc__ gene‐deficient mice. The present study was designed to investigate the combined effects of COX‐1 and COX