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Cowden's disease (multiple hamartoma and neoplasia syndrome) treated with isotretinoin

✍ Scribed by Lazar, Andrew P.; Lazar, Paul

Book ID: 122572012
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 877 KB
Volume: 14
Category: Article
ISSN: 1097-6787
DOI: 10.1016/S0190-9622(86)80400-5

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Cowden disease (CD) is a rare, autosomal dominant inherited cancer syndrome characterized by multiple benign and malignant lesions in a wide spectrum of tissues. While individuals with CD have an increased risk of breast and thyroid neoplasms, the primary features of CD are hamartomas. The gene for