Cover Picture: The Chemistry of Wine Polyphenolic C-Glycosidic Ellagitannins Targeting Human Topoisomerase II (Chem. Eur. J. 22/2005)

✍ Scribed by Stéphane Quideau; Michael Jourdes; Dorothée Lefeuvre; Danièle Montaudon; Cédric Saucier; Yves Glories; Patrick Pardon; Philippe Pourquier

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 159 KB
• Volume: 11
• Category: Article
• ISSN: 0947-6539
• DOI: 10.1002/chem.200590069

✦ Synopsis

The chemistry of oak‐derived NHTP‐bearing C‐glycosidic ellagitannins found in wine is reported by S. Quideau et al. in their Full Paper on page 6503 ff. These natural products are extracted by the wine solution during aging in barrels and have the capability to combine covalently by means of substitution reactions with a variety of grape‐derived nucleophilic species. The condensation products thus obtained can evidently contribute to the modulation of wine organoleptic properties, as well as possessing pharmacologically relevant activities.