✦ LIBER ✦

Cover Picture: Rational Design of Highly Active and Selective Ligands for the α5β1 Integrin Receptor (ChemBioChem 9/2008)

✍ Scribed by Dominik Heckmann; Axel Meyer; Burkhardt Laufer; Grit Zahn; Roland Stragies; Horst Kessler

Book ID: 102790068
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 751 KB
Volume: 9
Category: Article
ISSN: 1439-4227
DOI: 10.1002/cbic.200890032

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Rational Design of Highly Active and Sel

Rational Design of Highly Active and Selective Ligands for the α5β1 Integrin Receptor

✍ Dominik Heckmann; Axel Meyer; Burkhardt Laufer; Grit Zahn; Roland Stragies; Hors 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 735 KB

## Abstract The inhibition of integrin function is a major challenge in medicinal chemistry. Potent ligands are currently in different stages of clinical trials for the antiangiogenic therapy of cancer and age‐related macula degeneration (AMD). The subtype α5β1 has recently been drawn into the focu

Probing Integrin Selectivity: Rational D

Probing Integrin Selectivity: Rational Design of Highly Active and Selective Ligands for the α5β1 and αvβ3 Integrin Receptor

✍ Dominik Heckmann; Axel Meyer; Luciana Marinelli; Grit Zahn; Roland Stragies; Hor 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 323 KB 👁 2 views