Cover Picture: Iron-Catalyzed Aryl–Aryl Cross-Couplings with Magnesium-Derived Copper Reagents (Angew. Chem. Int. Ed. 11/2005)

✍ Scribed by Ioannis Sapountzis; Wenwei Lin; Christiane C. Kofink; Christina Despotopoulou; Paul Knochel

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 103 KB
• Volume: 44
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200590033

✦ Synopsis

Aryl–aryl cross‐couplings are among the most important CC bond‐forming reactions. Catalysts for this reaction tend to be expensive (Pd) or toxic (Ni). Fe salts are not usually employed as they promote homocoupling of the aryl magnesium reagent. In their Communication on page 1654 ff., P. Knochel and co‐workers report an efficient and environmentally benign [Fe(acac)~3~]‐catalyzed cross‐coupling of organocopper species ArCu(CN)MgCl with aryl iodides to give a wide range of polyfunctional biphenyl compounds in 50–93 % yield.