Herceptin–Platinum(II) Binding Complexes
✍
Jian Gao; Ya Guang Liu; Renbin Liu; Ralph A. Zingaro
📂
Article
📅
2008
🏛
John Wiley and Sons
🌐
English
⚖ 640 KB
## Abstract We report a new series of Herceptin–platinum(II) binding complexes, Her–__n__LPt^II^ (Her denotes Herceptin; L denotes diamino ligands and L=L1–L4; __n__=1, 5, or 10). Solution chemistry studies have shown that these complexes are stable under physiological conditions (pH 7.4 in PBS). T