Cover Picture: Eur. J. Immunol. 5/10

✍ Scribed by Yunying Chen; Fredrik Wermeling; Johanna Sundqvist; Ann-Beth Jonsson; Karl Tryggvason; Timo Pikkarainen; Mikael C. I. Karlsson

• Book ID: 102165087
• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 280 KB
• Volume: 40
• Category: Article
• ISSN: 0014-2980
• DOI: 10.1002/eji.201090023

✦ Synopsis

Abstract

This issue's cover image is provided by Chen et al., the authors of “A regulatory role for macrophage class A scavenger receptors in TLR4‐mediated LPS responses” (pp. 1451–1460). The image depicts immunofluorescent staining of mouse spleen frozen sections and demonstrates that FITC‐conjugated heat‐killed E. coli are efficiently captured by spleen marginal zone macrophages – a process that is facilitated by MARCO expressed on macrophages.