Cover Picture: Design and Non-Covalent DNA Binding of Platinum(II) Metallacalix[4]arenes (Chem. Eur. J. 18/2007)

✍ Scribed by Miguel A. Galindo; David Olea; M. Angustias Romero; Julio Gómez; Pedro del Castillo; Michael J. Hannon; Alison Rodger; Félix Zamora; Jorge A. R. Navarro

• Book ID: 101837162
• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 338 KB
• Volume: 13
• Category: Article
• ISSN: 0947-6539
• DOI: 10.1002/chem.200790062

✦ Synopsis

Metallacalixarenes were bound to DNA in a supramolecular fashion to induce a series of unprecedented sequential conformational changes. Clear noncovalent interactions between platinum‐containing metallacalix[4]arenes and calf thymus DNA are described by M. J. Hannon, A. Rodger, F. Zamora, J. A. R. Navarro et al. in their Full Paper on page 5075 ff. These interactions were expected, and were deduced from spectroscopic and atomic force microscopy studies.