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Cover Picture: ChemBioChem 6/2002

✍ Scribed by Tsuyoshi Takahashi; Akihiko Ueno; Hisakazu Mihara

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 19 KB
Volume: 3
Category: Article
ISSN: 1439-4227
DOI: 10.1002/1439-7633(20020603)3:6<481::aid-cbic481>3.0.co;2-n

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The cover picture shows bovine rhodopsin, the first G-protein-coupled receptor (GPCR) structure determined at atomic resolution. It is embedded into the cell membrane with the conserved seven transmembrane helices. Rhodopsin is unique among GPCRs due to its activation mechanism: The covalently bound