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Cover Picture: A Mass Spectrometric and Molecular Modelling Study of Cisplatin Binding to Transferrin (ChemBioChem 10/2005)

โœ Scribed by Isam Khalaila; Claire S. Allardyce; Chandra S. Verma; Paul J. Dyson


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
21 KB
Volume
6
Category
Article
ISSN
1439-4227

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A Mass Spectrometric and Molecular Model
โœ Isam Khalaila; Claire S. Allardyce; Chandra S. Verma; Paul J. Dyson ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 256 KB

## Abstract __A combination of mass spectrometry, UV/Vis spectroscopy and molecular modelling techniques have been used to characterise the interaction of cisplatin with human serum transferrin (Tf). Mass spectrometry indicates that cisplatin binds to the hydroxy functional group of threonine 457,