Covariate Effects on the Apparent Clearance of Tacrolimus in Paediatric Liver Transplant Patients Undergoing Conversion Therapy
✍ Scribed by Dr María Jose García Sánchez, Cecilia Manzanares, Dolores Santos-Buelga, Alberto Blázquez, Javier Manzanares, Pedro Urruzuno, Enrique Medina
- Book ID
- 119926328
- Publisher
- Springer International Publishing AG
- Year
- 2001
- Tongue
- English
- Weight
- 162 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0312-5963
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📜 SIMILAR VOLUMES
It has been known for several decades that thromboelastographic analysis of the blood of patients undergoing liver transplantation may show a heparin-like effect (HLE) at the time of reperfusion. However, the prevalence of HLE and the origin of these heparin-like substances remain largely unstudied.
As ursodeoxycholic acid (UDCA) delays the need for transplantation, this could result in patients with more comorbid disease, therefore more likely to have a worse outcome posttransplantation. The aim of this study is to compare posttransplantation outcome in patients who received UDCA versus placeb