An algorithm based on the technique of combinatorial minimization is used for the semi-automated assignment of multidimensional heteronuclear spectra. The program (ALFA) produces the best assignment compatible with the available input data. Even partially misleading or missing data do not seriously
Covariance NMR in higher dimensions: application to 4D NOESY spectroscopy of proteins
✍ Scribed by David A. Snyder; Fengli Zhang; Rafael Brüschweiler
- Publisher
- Springer Netherlands
- Year
- 2007
- Tongue
- English
- Weight
- 422 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0925-2738
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## Abstract The ^1^H and ^13^C NMR spectra of __d__‐biotin were observed at 400 and 100 MHz, respectively. Various types of two‐dimensional NMR spectroscopy were performed to assign the spectra. The previous assignment of ^13^C NMR spectrum of __d__‐biotin reported by Bradbury and Johnson was modif